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Uses

Tramadol is used similarly to codeine, to treat moderate to moderately severe pain and most types of neuralgia, including trigeminal neuralgia. Tramadol is somewhat pharmacologically similar to levorphanol (albeit with much lower m-agonism),
as both opioids are also NMDA-antagonists which also have SNRI activity (other such opioids to do the same are dextropropoxyphene (Darvon) & M1-like molecule tapentadol (Nucynta, a new synthetic atypical opioid made to mimic the
agonistic properties of tramadol's metabolite, M1(O-Desmethyltramadol). Tramadol is also molecularly similar to Effexor and has similar SNRI effects, with antinociceptive effects also observed. It has been suggested that tramadol could be
effective for alleviating symptoms of depression, anxiety, and phobias because of its action on the noradrenergic and serotonergic systems, such as its "atypical" opioid activity. However, health professionals have not endorsed its use
for these disorders, claiming it may be used as a unique treatment (only when other treatments failed), and must be used under the control of a psychiatrist.

Availability and usage

Tramadol is usually marketed as the hydrochloride salt (tramadol hydrochloride); the tartrate is seen on rare occasions, and rarely (in the US at least) tramadol is available for both injection (intravenous and/or intramuscular) and oral administration. The most well known dosing unit is the 50 mg generic tablet made by several manufacturers. It is also commonly available in conjunction with APAP (Paracetamol, Acetaminophen) as Ultracet, in the form of a smaller dose of 37.5 mg tramadol and 325 mg of APAP. The solutions suitable for injection are used in patient-controlled analgesia pumps under some circumstances, either as the sole agent or along with another agent such as morphine.
Tramadol comes in many forms, including:

* capsules (regular and extended release)
* tablets (regular, extended release, chewable, low-residue and/or uncoated tablets that can be taken by the sublingual and buccal routes)
* suppositories
* effervescent tablets and powders
* ampules of sterile solution for SC, IM, and IV injection
* preservative-free solutions for injection by the various spinal routes (epidural, intrathecal, caudal, and others)
* powders for compounding
* liquids both with and without alcohol for oral and sub-lingual administration, available in regular phials and bottles, dropper bottles, bottles with a pump similar to those used with liquid soap and phials with droppers built into the cap
* tablets and capsules containing (acetaminophen/APAP), aspirin and other agents.


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1911sr

I guess I have to ignore that jerk posting the spam above me, but.................

This is what my Dad carried on the place for as long as I can remember.
44-40 saddle carbine and a 44-40 revolver.



And this is Dad on his old saddlehorse Shonkin @1979. You can see the 44-40 in the scabbard but the revolver is on his right hip.



And this is the old homestead where us kids were born and raised.

gripper

Beautiful shot of the family house...BTW what IS the point of the spamming?They're annoying,but beyond that;what so they accomplish?

1911sr

Its a simple marketing logic. If they do 1,000 spam posts and got just 10 interested people in whatever they're selling, then it's justified to them. It opens a lot of other doors with just those 10 people and once they're registered like here, and the webmaster does nothing about it, they simply continue. Its no good to jsut delete the posts. The accounts have to be deleted and if the ip address is out of the country, that IP has to be banned.
It just takes a little time for an alert mod and an interested webmaster.

1911sr

And one other thing. New registrations must be routed through the mod.
It only takes a minute to determine if the new account is a spammer or not.

money30

This is a topic that has generated some interest over at Gabe Suarez forum, and after some reading, it has my curiosity piqued as well.

For those who live in legislation-restricted areas, or maybe even for those who prefer such a platform, the lever action seems to have some interesting advantages.

Was curious as to what you all thought about the caliber discussion: i.e., .357, .44, or traditional .30-30. To my mind, it would be more beneficial to have a .44 or .357, reasoning being that the gun could do double duty with .38 or .44 Special.

Garand

Personally I would go with .44 or .357 as the carbines based on the Winchester 73 and the Winchester 92 have far smoother actions than those based on the Winchester 94 with centerfire rifle cartridges.